Fertility Regulation in Male Rats by Implemented Tetraazamacrocyclic Compounds of Iron(II): Synthetic, Spectroscopic, and Applied Aspects With Toxicological Screening
نویسندگان
چکیده
Antifertility and histopathological investigations were carried out on reproductive organs of male albino rats induced by tetraazamacrocyclic complexes of iron(II). The complexes were synthesized by the template condensation of 1,2-diaminoethane, 1,3-diaminopropane with succinic acid and phthalic acid in 2 : 2 molar ratios which are abbreviated as [Fe(TAML(n))OAc] (n = 1 or 2 and TAML(n) represents tetraazamacrocyclic ligand). The complexes have been characterized by elemental analysis, conductivity measurements, IR, and electronic spectra.
منابع مشابه
Fertility Inhibitors Macrocyclic Complexes of Bivalent Manganese: Synthetic, Spectroscopic and Medicinal Approach
The modern physico-chemical, spectroscopic and biochemical methods have proved an important tool to elucidate the constitution of transition metal complexes. This paper presents a brief account of the synthesis, spectroscopic and medicinal aspects of tetraazamacrocyclic compounds of manganese(II). Sixteen to eighteen membered tetraamide macrocyclic ligands DTTD(1) and DTTD(2) have been synthesi...
متن کاملAssessement of Reproductive Toxicity Induced by Deltamethrin In Male Albino Rats
Introduction: Pyrethroids are important insecticides because of their high activity and low mammalian toxicity. Some studies have demonstrated that these insecticides, especially compounds with an -cyano group, produce toxic effects on various biological systems. Deltamethrin (DTM) is a Type II synthetic pyrethroid insecticide containing -cyano group and is used worldwide in agriculture, ho...
متن کاملAntifungal, Antibacterial and Antifertility Activities of Biologically Active Macrocyclic Complexes of Tin(II)
Synthetic, structural and biological aspects of tetraazamacrocyclic complexes of Tin(II) have been described. The complexes were characterized by elemental analysis, molecular weight determination conductance measurements and electronic, infrared, H,C and Sn NMR spectral studies. Ligand and their unsymmetrical complexes have been tested for their antimicrobial effects on several pathogenic fung...
متن کاملAcute toxicity investigation regarding clinical and pathological aspects following repeated oral administration of iron oxide nanoparticles in rats
Iron oxide nanoparticles (IONPS) have potential different applications in nanomedicine. These new applications of IONPS have raised exposure risk of this nanomaterials to humans. Up to now, all aspects of IONPS toxicity are not fully clear following animal’s exposure with these novel compounds. This study aimed to investigate the acute toxicity effects of IONPS in laboratory animals regarding p...
متن کاملSynthesis, Characterization and in Vitro Antimicrobial Screening of the Xanthate Derivatives and their Iron(II) Complexes
Seven reported xanthate ligands and their new Fe(II) complexes of formulaNa[Fe(R-OCSS)3], where R is ethyl-, propyl-, butyl-, pentyl-, Hexyl-, heptyl- and octyl-xanthate have been synthesized. They have been characterized using elemental analysis, molar conductance, FT-IR, UV-Vis and 1H NMR spectroscopic techniques and melting-, decomposition-points for ligand...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Bioinorganic chemistry and applications
دوره 2006 شماره
صفحات -
تاریخ انتشار 2006